Director: Andrea Troxel, ScD
The Biostatistics Core provides expert biostatistical guidance in the design, conduct, and analysis of research projects conducted by cancer center members, and offers training in the fundamentals of design and analysis to the Penn cancer research community. Specific areas of expertise include study design; use of research computing for database development, data management, and study monitoring; and analysis of basic, translational, clinical, and population-based research. Core personnel are prepared not only to apply existing methods of design and analysis, but also to modify or develop new methods to address novel design and analysis issues arising in cancer research projects. Collaborations emphasize establishing valid and testable hypotheses, identifying appropriate outcome measures, determining and applying optimal study designs, and examining power and sample size. Core members are also active in the Clinical Trials Scientific Review and Monitoring Committee, providing a thorough review of all proposed protocols, with the aim of ensuring that all clinical protocols are designed to efficiently and ethically achieve their clinical and translational objectives. Finally, the Core provides a range of data-centered services including data resource needs assessment; evaluation, selection, and deployment of commercial software tools; development of specialized software systems; support for data collection, management, and integration; guidance on computing hardware support; and education and training.
Andrea Troxel, ScD