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Amit Maity, MD, PhD

Amit Maity, MD, PhD Physician

Director of Quality Assurance/ Quality Improvement, Department of Radiation Oncology, HUP
Vice Chair, Clinical Division
Professor of Radiation Oncology at the Hospital of the University of Pennsylvania

Dr. Maity is a Penn Medicine employed physician.

Clinical Specialties

Specialty:

  • Radiation Oncology

Programs & Centers:

  • Cancer
    • Leukemia Program
    • Lymphoma Program
  • Radiation Oncology

Board Certification:

  • Internal Medicine, 1988
  • Radiation Oncology, 1992

Clinical Expertise:

  • Acute Leukemia
  • Blood Cancer
  • Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)
  • Chronic Myeloid Leukemia (CML)
  • Leiomyosarcoma (LMS)
  • Leukemia
  • Lung Cancer
  • Lymphoma
  • Mediastinal Tumors
  • Metastasis Cancer
  • Non-Hodgkin Lymphoma
  • Radiation Treatment

Practice Locations and Appointments

  • Penn Radiation Oncology

    Perelman Center for Advanced Medicine Concourse Level 3400 Civic Center Boulevard Philadelphia, PA 19104 800-789-PENN (7366)

    A facility of the Hospital of the University of Pennsylvania

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Care
  • Rail Road Medicare / Palmetto GBA
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: Boston University School of Medicine
Residency: Mount Sinai Medical Center
Residency: Hospital of the University of Pennsylvania
Fellowship: Hospital of the University of Pennsylvania
Fellowship: Johns Hopkins Hospital

Memberships

American Association for Cancer Research, National American Board of Radiology, National American Board of Radiology, National Radiation Research Society, National

Hospital Affiliation

Dr. Maity is a Penn Medicine employed physician.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.

Research

Description of Research Expertise:

RESEARCH INTERESTS:
My laboratory based research focuses on developing strategies of improving the radiation response, using agents that modify the tumor microenvironment and alter cellular signaling. In particular we have focused on the PI3K/mTOR pathway, which is upregulated in many human cancers. Our research suggest that inhibition of this pathway can increase the intrinsic sensitivity of tumor cells to radiation and also decrease tumor oxygenation.
My clinical research focuses on using hypofractionated radiation to potentiate the action of immune checkpoint inhibitors in patient with metastatic solid tumors including melanoma, non small-lung cancer, and breast cancer.

Selected Publications:

Cerniglia George J, Dey Souvik, Gallagher-Colombo Shannon M, Daurio Natalie A, Tuttle Stephen, Busch Theresa M, Lin Alexander, Sun Ramon, Esipova Tatiana V, Vinogradov Sergei A, Denko Nicholas, Koumenis Constantinos, Maity Amit: The PI3K/Akt Pathway Regulates Oxygen Metabolism via Pyruvate Dehydrogenase (PDH)-E1a Phosphorylation. Molecular cancer therapeutics 14 (8): 1928-38,2015.

Hill-Kayser Christine E, Gabriel Peter, Volz Edna, Lustig Robert A, Tochner Zelig, Hahn Stephen M, Maity Amit: Factors associated with event reporting in the pediatric radiation oncology population using an electronic incident reporting system. Practical radiation oncology : 2015.

Lin Alexander, Maity Amit: Molecular Pathways: A Novel Approach to Targeting Hypoxia and Improving Radiotherapy Efficacy via Reduction in Oxygen Demand. Clinical cancer research : an official journal of the American Association for Cancer Research 21 (9): 1995-2000,2015.

Gabriel Peter E, Volz Edna, Bergendahl Howard W, Burke Sean V, Solberg Timothy D, Maity Amit, Hahn Stephen M: Incident learning in pursuit of high reliability: implementing a comprehensive, low-threshold reporting program in a large, multisite radiation oncology department. Joint Commission journal on quality and patient safety / Joint Commission Resources 41 (4): 160-8,2015.

Gandhi SJ, Minn A, Vonderheide RH, Wherry EJ, Hahn SM, Maity A: Awakening the immune system with radiation: Optimal dose and fractionation. Cancer letters : 2015.

Twyman-Saint Victor C, Rech AJ, Maity A, Rengan R, Pauken KE, Stelekati E, Benci JL, Xu B, Dada H, Odorizzi PM, Herati RS, Mansfield KD, Patsch D, Amaravadi RK, Schuchter LM, Ishwaran H, Mick R, Pryma DA, Xu X, Feldman MD, Gangadhar TC, Hahn SM, Wherry EJ, Vonderheide RH, Minn AJ: Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer. Nature : 2015.

Descaris c, Woodhouse K, Volz E, Gabriel P, Suneja G, Maity A, Hahn S: Examining Patient Perceptions of Quality and Safety in a Large Radiation Oncology Department 2015 American Society for Radiation Oncology (ASTRO) Annual Meeting, poster presentation : 2015.

Rech AJ, Twyman-Saint Victor C, Maity A, Rengan R, Pauken KE, Stelekati E, Benci J, Xu B, Dada H, Odorizzi PM, Herati RS, Mansfield KD, Patsch D, Amaravadi RK, Schuchter LM, Ishwaran H, Mick R, Pryma D, Xu X, Feldman MD, Gangadhar TC, Hahn SM, Wherry EJ, Minn AJ, Vonderheide RH: Radiation and dual immune checkpoint blockade overcome tumor resistance and distinctly improve immunity Proceedings of the american association for cancer research annual meeting : 2015.

Cerniglia GJ, Dey S, Gallagher-Colombo SM, Daurio N, Tuttle S, Busch TM, Lin A, Esipova TV, Vinogradov SA, Koumenis C, Maity A: PI3K/Akt inhibition decreases oxygen consumption In tumor cells by phosphorylating and inactivating pyruvate dehydrogenase PDH E1a subunit Proceedings of the american association for cancer research annual meeting : 2015.

Woodhouse K, Volz E, Bellerive M, Gabriel P, Maity A, Hahn S, Vapiwala N: The Implementation and Assessment of a Quality and Safety Culture Education Program in a Large Radiation Oncology Department 2015 American Society for Radiation Oncology (ASTRO) Annual Meeting, poster presentation : 2015.

View all publications

Academic Contact Info

TRC 2West
3400 Civic Center Blvd.

Philadelphia, PA 19104
Phone: (215) 662-3759
Fax: (215) 349-5445
Patient appointments: 800-789-PENN (7366)

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