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Amit Maity, MD, PhD

Amit Maity, MD, PhD Physician

Director of Quality Assurance/ Quality Improvement, Department of Radiation Oncology, HUP
Professor of Radiation Oncology at the Hospital of the University of Pennsylvania

Dr. Maity is a Penn Medicine employed physician.

Clinical Specialties

Specialties:

  • Radiation Oncology

Programs & Services:

  • Cancer
    • Leukemia
    • Lymphoma
  • Radiation Oncology

Board Certification:

  • Internal Medicine, 1988
  • Radiation Oncology, 1992

Conditions & Treatments:

  • acute leukemia
  • adolescent physicals (camp)
  • adolescent physicals (school)
  • adolescents - well child visit
  • Asthma
  • Blood Cancer
  • cancer - metastasis
  • cholesterol
  • chronic leukemia
  • contraception
  • cutaneous lymphoma
  • cutaneous T-cell lymphoma
  • diabetic care
  • driver's license exam
  • hypothyroidism
  • immunizations
  • leiomyosarcoma
  • Leukemia
  • Lung Cancer
  • lung cancer - mediastinal tumors
  • Lymphoma
  • non-Hodgkin's lymphoma
  • Obesity
  • pap smear
  • preconception counseling
  • prenatal care
  • Radiation Treatment
  • Sexually Transmitted Diseases (STD)
  • Urinary Tract Infection
  • weight management

Practice Locations and Appointments

  • Penn Radiation Oncology

    Perelman Center for Advanced Medicine Concourse Level 3400 Civic Center Boulevard Philadelphia, PA 19104 800-789-PENN (7366)

    A facility of the Hospital of the University of Pennsylvania

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Care
  • Rail Road Medicare / Palmetto GBA
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: Boston University School of Medicine
Residency: Mount Sinai Medical Center
Residency: Hospital of the University of Pennsylvania
Fellowship: Hospital of the University of Pennsylvania
Fellowship: Johns Hopkins Hospital

Memberships

American Association for Cancer Research, National American Board of Radiology, National American Board of Radiology, National Radiation Research Society, National Radiologic Society of North America (RSNA) Radiation Oncology study section, National

Affiliation

Dr. Maity is a Penn Medicine employed physician.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.

Research

Research Interests:

RESEARCH INTERESTS:
My laboratory based research focuses on developing strategies of improving the radiation response, using agents that modify the tumor microenvironment and alter cellular signaling. In particular we have focused on the PI3K/mTOR pathway, which is upregulated in many human cancers. Our research suggest that inhibition of this pathway can increase the intrinsic sensitivity of tumor cells to radiation and also decrease tumor oxygenation.
My clinical research focuses on using hypofractionated radiation to potentiate the action of immune checkpoint inhibitors in patient with metastatic solid tumors including melanoma, non small-lung cancer, and breast cancer.

Selected Publications:

Gandhi SJ, Minn A, Vonderheide RH, Wherry EJ, Hahn SM, Maity A: Awakening the immune system with radiation: Optimal dose and fractionation. Cancer letters : 2015.

Twyman-Saint Victor C, Rech AJ, Maity A, Rengan R, Pauken KE, Stelekati E, Benci JL, Xu B, Dada H, Odorizzi PM, Herati RS, Mansfield KD, Patsch D, Amaravadi RK, Schuchter LM, Ishwaran H, Mick R, Pryma DA, Xu X, Feldman MD, Gangadhar TC, Hahn SM, Wherry EJ, Vonderheide RH, Minn AJ: Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer. Nature : 2015.

Cerniglia GJ, Dey S, Gallagher-Colombo SM, Daurio N, Tuttle S, Busch TM, Lin A, Esipova TV, Vinogradov SA, Koumenis C, Maity A: PI3K/Akt inhibition decreases oxygen consumption In tumor cells by phosphorylating and inactivating pyruvate dehydrogenase PDH E1a subunit Proceedings of the american association for cancer research annual meeting : 2015.

Rech AJ, Twyman-Saint Victor C, Maity A, Rengan R, Pauken KE, Stelekati E, Benci J, Xu B, Dada H, Odorizzi PM, Herati RS, Mansfield KD, Patsch D, Amaravadi RK, Schuchter LM, Ishwaran H, Mick R, Pryma D, Xu X, Feldman MD, Gangadhar TC, Hahn SM, Wherry EJ, Minn AJ, Vonderheide RH: Radiation and dual immune checkpoint blockade overcome tumor resistance and distinctly improve immunity Proceedings of the american association for cancer research annual meeting : 2015.

Welsh JW, Seyedin SN, Cortez MA, Maity A, Hahn SM: Galectin-1 and immune suppression during radiotherapy. Clinical cancer research : an official journal of the American Association for Cancer Research 20 (24): 6230-2,2014.

Alonso-Basanta M, Fang P, Maity A, Hahn SM, Lustig RA, Dorsey JF: A Phase I Study of Nelfinavir Concurrent with Temozolomide and Radiotherapy in Patients with Glioblastoma Multiforme. Journal of Neurooncology 116 (2): 365-72,2014.

Thompson RF, Maity A: Radiotherapy and the tumor microenvironment: mutual influence and clinical implications. Advances in Experimental Medicine and Biology 772 : 147-65,2014.

View all publications

Academic Contact Info

TRC 2West
3400 Civic Center Blvd.

Philadelphia, PA 19104
Phone: (215) 662-3759
Fax: (215) 349-5445
Patient appointments: 800-789-PENN (7366)

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