Find a Provider

Angela DeMichele, MD, MSCE Physician

Co-Leader, Breast Cancer Research Program
Alan and Jill Miller Associate Professor in Breast Cancer Excellence
Associate Professor of Epidemiology in Biostatistics and Epidemiology

Dr. DeMichele is a Penn Medicine employed physician.

Clinical Specialties


  • Medicine
    • Medical Oncology

Programs & Services:

  • Cancer
    • Breast Cancer
    • LIVESTRONG™ Cancer Survivorship Center

Board Certification:

  • Medical Oncology, 1998

Conditions & Treatments:

  • Breast Cancer
  • Ductal Carcinoma in Situ (DCIS)
  • Inflammatory Breast Cancer (IBC)
  • Integrative Medicine
  • Invasive (Infiltrating) Ductal Carcinoma (IDC)
  • Invasive (Infiltrating) Lobular Carcinoma (ILC)
  • Male Breast Cancer
  • Other types of Breast Cancer
  • Triple-Negative Breast Cancer

Clinical Interests

breast cancer, neoadjuvant therapy, menopausal symptoms related to cancer, cancer survivorship

Practice Locations and Appointments

  • Rena Rowan Breast Center

    Abramson Cancer Center Perelman Center for Advanced Medicine, West Pavilion, 3rd Floor 3400 Civic Center Boulevard Philadelphia, PA 19104 800-789-PENN (7366)

    A facility of the Hospital of the University of Pennsylvania

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Care
  • Rail Road Medicare / Palmetto GBA
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: Washington University
Residency: Hospital of the University of Pennsylvania
Fellowship: University of Bologna School of Medicine
Fellowship: Hospital of the University of Pennsylvania


American Association of Cancer Research, National American Board of Internal Medicine, National American College of Epidemiology, National American College of Physicians, National American Society of Breast Disease, National American Society of Clinical Oncology, National Expedition Inspiration Fund for Breast Cancer Research, National Medical Advisory Board, Living Beyond Breast Cancer, National


Dr. DeMichele is a Penn Medicine employed physician.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.


Research Interests:

breast cancer, biomarkers, clinical trials, pharmacogenetics, cytokines, host immunogenetics, cancer survivorship, molecular epidemiology

Selected Publications:

Tan AS, Nagler RH, Hornik RC, DeMichele A: Evolving information needs among colon, breast, and prostate cancer survivors: results from a longitudinal mixed- effects analysis Cancer Epidemiol Biomarkers Prev 24 : 1071-8,2015.

Brier MJ, Chambless D, Gross R, Su HI, DeMichele A, Mao JJ: Association between self-report adherence measures and oestrogen supression among breast cancer survivors on aromatase inhibitors European Journal of Cancer Epub ahead of print : 2015.

Ou Y, Weinstein SP, Conant EF, Englander S, Da X, Gaonkar B, Hsieh MK, Rosen M, DeMichele A, Davatzikos C, Kontos D: Deformable registration for quantifying longitudinal tumor changes during neoadjuvant chemotherapy Magnetic Resonance Medicine 73 (6): 2343-56,2015.

Bauml J, Chen L, Chen J, Boyer J, Kalos M, Li SQ, DeMichele A, Mao JJ: Arthralgia among women taking aromatase inhibitors: is there a shared inflammatory mechanism with comorbid fatigue and insomnia? Breast Cancer Research 17 : 89,2015.

Ashraf A, Gaonkar B, Mies C, DeMichele A, Rosen M, Davatzikos C, Kontos D: Breast DCE-MRI kinetic heterogeneity tumor markers: Preliminary associates with neoadjuvant chemotherapy response Translational Oncology 8 (3): 154-62,2015.

Chung SH, Feldman MD, Martinez D, Kim H, Putt ME, Busch DR, Tchou J, Czerniecki BJ, Schnall MD, Rosen MA, DeMichele A, Yodh AG, Choe R: Macroscopic optical physiological parameters correlate with microscopic proliferation and vessel area breast cancer signatures Breast Cancer Research 17 : 72,2015.

Datta J, Berk E, Xu S, Fitzpatrick E, Rosemblit C, Lowenfeld, Goodman N, Lewis DA, Zhang PJ, Fisher C, Roses RE, DeMichele A, Czerniecki BJ: Anti- HER2 CD4(+) T-helper type 1 response is a novel immune correlate to pathologic response following neoadjuvant therapy in HER2- positive breast cancer Breast Cancer Research 17 : 71,2015.

Melichar B, Adenis A, Lockhart AC, Bennouna J, Dees EC, Kayaleh O, Obermannova R, DeMichele A, Zatloukal P, Zhang B, Ullmann CD, Schusterbauer C.: Safety and activity of alisertib, an investigational aurora kinase A inhibitor, in patients with breast cancer, small cell lung cancer, non small cell lung cancer, head and neck squamous carcinoma and gastro-oesophageal adenocarcinoma: a five-arm phase 2 study Lancet Oncology (4): 395-405,2015.

DeMichele A, Clark AS, Tan KS, Heitjan DF, Gramlich K, Gallagher M, Lal P, Feldman M, Zhang P, Colameco C, Lewis D, Langer M, Goodman N, Domchek S, Gogineni K, Rosen M, Fox K, O'Dwyer P: CDK4/6 Inhibitor Palbociclib (PD0332991) in Rb+ Advanced Breast Cancer: Phase II Activity, Safety and Predictive Biomarker Assessment Clinical Cancer Research 21 (5): 995-1001,2015.

White J, DeMichele A: Neoadjuvant therapy for breast cancer: controversies in clinical trial design and standard of care American Society of Clinical Oncology Education Book 35 : 17-23,2015.

Academic Contact Info

Perelman Center for Advanced Medicine
3 West Pavilion
3400 Civic Center Boulevard

Philadelphia, PA 19104
Phone: (215) 349-5730
Fax: (215) 615-3349
Patient appointments: 800-789-PENN (7366)

Related Links