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Caryn Lerman, PhD

Caryn Lerman, PhD Researcher

Professor of Psychology in Psychiatry

Dr. Lerman is a Penn Medicine employed provider.

Clinical Specialties

Specialties:

  • Psychiatry

Programs & Services:

  • Cancer

Clinical Interests

Licensed clinical psychologist

Memberships

Academy of Behavioral Medicine Research, American Association for Cancer Research, American College of Neuropsychopharmacology, International American Psychological Association, External Advisory Board, Indiana University, Indiana Institute for Personalized Medicine, National External Advisory Board, MD Anderson Cancer Center, National External Advisory Board, UC Irvine, Chao Family Comprehensive Cancer Center, National External Advisory Board, USC, Norris Cancer Center, National Institute of Medicine of the National Academies, National Memorial Sloan Kettering Cancer Center, Board of Scientific Counselors, National Society for Neuroscience, International Society for Research on Nicotine and Tobacco, International University of North Carolina Lineberger Cancer Center, External Scientific Advisory Board, National

Affiliation

Dr. Lerman is a Penn Medicine employed provider.

Research

Research Interests:

Dr. Lerman’s research interests focus on translating research in neuroscience, pharmacology, genetics and behavioral science to develop improved interventions for health risk behavior change.

Selected Publications:

Wang Z, Faith M, Patterson F, Tang K, Kerrin K, Wileyto EP, Detre JA, Lerman C.: Neural substrates of abstinence-induced cigarette cravings in chronic smokers. Journal of Neuroscience 27 : 14030-14040,2007.

Loughead J, Wileyto EP, Valdez NJ, Sanborn P, Tang K, Strasser AA, Ruparel K, Ray R, Gur RC, Lerman C.: Effect of abstinence challenge on brain function and cognition in smokers differs by COMT genotype. Molecular Psychiatry 14 (8): 820-826,2009.

Loughead J, Ray R, Wileyto EP, Ruparel K, Sanborn P, Siegel S, Gur RC, Lerman C.: Effects of the alpha4beta2 partial agonist varenicline on brain activity and working memory in abstinent smokers. Biological Psychiatry 67 (8): 715-721,2010.

Schnoll RA, Patterson F, Wileyto EP, Heitjan D, Shields AE, Asch D, Lerman C.: Effectiveness of extended duration transdermal nicotine therapy: a randomized trial. Annals of Internal Medicine 152 (3): 144-151,2010.

Lerman C, Jepson C, Wileyto EP, Patterson F, Schnoll R, Mroziewicz M, Benowitz N, Tyndale RF.: Genetic variation in nicotine metabolism predicts the efficacy of extended duration transdermal nicotine therapy. Clinical Pharmacology & Therapeutics 87 (5): 553-557,2010.

Ray R, Ruparel K, Newberg A, Wileyto EP, Loughead J, Divgi C, Blendy JA, Logan J, Zubieta JK, Lerman C.: Human mu opioid receptor (OPRM1 A118G) polymorphism is associated with brain mu opiod receptor binding potential in smokers. Proceedings of the National Academy of Sciences USA 108 (22): 9268-9273,2011.

Mrazek DA, Lerman C.: Pharmacogenomics: facilitating clinical implementation. Journal of the American Medical Association 306 (3): 304-305,2011.

Academic Contact Info

Center for Interdisciplinary Research on Nicotine Addiction (CIRNA)
3535 Market Street, Suite 4100

Philadelphia, PA 19104
Phone: (215) 746-7141
Fax: (215) 746-7140

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