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David C. Metz, MD

David C. Metz, MD Physician

Associate Chief for Clinical Affairs, GI Division
Co-Director, Esophagology and Swallowing Program
Co-Director, Neuroendocrine Tumor Center
Director, Acid-Peptic Program
Professor of Medicine at the Hospital of the University of Pennsylvania

Dr. Metz is a Penn Medicine employed physician.

About Dr. David C. Metz

Recognized annually in Philadelphia Magazine's Top Docs issue from 2004 through 2015

Recognized by America's Top Doctors, 2007, 2008, 2010, 2012-14

Recognized by Best Doctors in America 2003-2004, 2005-2006, 2007-2008, 2009-2010, 2011-2012, 2013-2014

Clinical Specialties


  • Medicine
    • Gastroenterology

Programs & Services:

  • Cancer
    • Anal Cancer
    • Colon Cancer
    • Esophageal Cancer
    • Gastrointestinal (GI) Cancer Risk Evaluation Program
    • Gastrointestinal Cancer Evaluation Center (GICEC)
    • Liver Cancer
    • Pancreatic Cancer
    • Rectal Cancer
    • Small Intestine Cancer
    • Stomach (Gastric) Cancer
  • Gastroenterology
    • Acid-Peptic Disorders
    • Endoscopy and GI Diagnosis
    • Esophageal and Swallowing Disorders
    • Gastrointestinal Cancer

Board Certification:

  • Gastroenterology, 1991
  • Internal Medicine, 1989

Conditions & Treatments:

  • Acid Peptic Disorders
  • Anal Cancer
  • Bile Duct Cancer
  • Celiac Disease
  • Colon Cancer
  • Esophageal Cancer
  • Gallbladder Cancer
  • Gastroesophageal Reflux Disease (GERD)
  • Gastrointestinal Carcinoid Tumor
  • gastrointestinal physiology testing
  • H. Pylori Infection
  • Liver Cancer
  • Neuroendocrine Tumors
  • neuroendocrine tumors of the bowel
  • neuroendocrine tumors of the pancreas
  • Pancreatic Cancer
  • Rectal Cancer
  • Small Intestine Cancer
  • Stomach (Gastric) Cancer
  • upper GI motility disorders

Practice Locations and Appointments

  • Gastroenterology

    Perelman Center for Advanced Medicine South Pavilion, 4th Floor 3400 Civic Center Boulevard Philadelphia, PA 19104 800-789-PENN (7366)

    A facility of the Hospital of the University of Pennsylvania

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Care
  • Rail Road Medicare / Palmetto GBA
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: University of the Witwatersrand Pulse Beat Medical School
Residency: Johannesburg General Hospital/Witwatersrand University
Residency: Albert Einstein Medical Center
Fellowship: Georgetown University Hospital
Fellowship: National Institutes of Health


ABIM Continuous Professional Development Program, National AGAI Nominating Committee, National American Board of Internal Medicine CPD Question-Writing Committee, National American College of Gastroenterology (ACG), National American Gastroenterological Association Distinguished Educator Award Selection Committee, National American gastroenterological Association EGD section, National American Gastroenterological Association EGD Section, National American Gastroenterological Association, National American Gastroenterological Association, National Division of Gastroenterology, University of Pennsylvania Clinical Practice Section Program Planning Committee, Local Division of Gastroenterology, University of Pennsylvania, Abstract Review (Dyspepsia and Acid-peptic and other gastroduodenal disorders, Local Division of Gastroenterology, University of Pennsylvania, Core Curriculum Task Force on Training in Acid Peptic Disease, Local National Board of Medical Examiners, National North American Neuroendocrine Tumor Society (NANETS) Executive Committee, National


Dr. Metz is a Penn Medicine employed physician.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Medicine Radnor: Has privileges to perform procedures.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.


Selected Publications:

Lau CT, Gefter WB, Metz DC: Radiographic appearance of a catheter-free wireless esophageal pH probe Am J Roentgenol 184 : S40-42,2005.

Shih GL, Brensinger C, Katzka DA, Metz DC: Postprandial esophageal integrated acidity is a reliable predictor of GERD Aliment Pharmacol Therap 21 : 1475-1482,2005.

Metz DC, Miner PB, Heuman DM, Chen Y, Sostek M: Comparison of the effects of intravenously and orally administered esomeprazole on acid output in patients with symptoms of gastro-esophageal reflux disease Aliment Pharmacol Therap 22 : 813-821,2005.

Metz DC, Comer GM, Soffer E, Forsmark CE, Cryer B, Chey W, Pisegna JR: Three year oral pantoprazole administration is effective for patients with Zollinger-Ellison syndrome and other hypersecretory conditions Aliment Pharmacol Therap 23 : 437-444,2006.

Pratha V, Hogan DL, Lynn RB, Field B, Metz DC: Intravenous Pantoprazole as Initial Treatment in Patients With Gastroesophageal Reflux Disease and a History of Erosive Esophagitis: A Randomized Clinical Trial Dig Dis Sci 51 : 1595-1601,2006.

Blonski WC, Shih GL, Brensinger CM, Katzka DA, Metz DC: Analysis of the acidity index and integrated intragastric acidity in 645 patients presenting with gastroesophageal reflux disease symptoms Sc J Gastroenterol 41 : 382-389,2006.

Yang YX, Lewis JD, Epstein S, Metz DC: Chronic proton pump inhibitor therapy and hip fracture risk JAMA 296 : 1595-1601,2006.

Lewis JD, Strom BL, Kimmel SE, Farrar J, Metz DC, Brensinger C, Nessel L, Localio AR: Predictors of recall of over-the-counter and prescription non-steroidal anti-inflammatory drug exposure Pharmacoepidemiol Drug Saf 15 : 39-45,2006.

Howden C, Metz DC, Hunt B, Majid V, Kukulka M, Amer F, Samra N.: Dose-Response Evaluation of the Antisecretory Effect of Continuous Infusion Intravenous Lansoprazole Regimens over 48 Hours Aliment Pharmacol Therap 23 : 975-984,2006.

Metz DC, Amer F, Hunt B, Majid V, Kukulka M.: Lansoprazole Regimens That Sustain Intragastric pH >6: An Evaluation of Intermittent Oral and Continuous IV Infusion Dosages Aliment Pharmacol Therap 23 : 985-995,2006.

View all publications

Academic Contact Info

University of Pennsylvania Health System
Division of Gastroenterology
3400 Civic Center Boulevard
Perelman Center for Advanced Medicine
7 South Pavilion

Philadelphia, PA 19104
Phone: (215) 662-3541
Fax: (215) 349-5915
Patient appointments: 800-789-PENN (7366)

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