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James D. Kolker, MD

James D. Kolker, MD Physician

Chief, Section of Radiation Oncology, Pennsylvania Hospital
Medical Director, CyberKnife
Clinical Assistant Professor of Radiation Oncology

Dr. Kolker is a Penn Medicine employed physician.

Clinical Specialties


  • Radiation Oncology

Programs & Services:

  • Cancer
  • Radiation Oncology

Board Certification:

  • Internal Medicine, 1985
  • Radiation Oncology, 1993

Conditions & Treatments:

  • Radiation Treatment

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Care
  • Rail Road Medicare / Palmetto GBA
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: Jefferson Medical College
Residency: Roger Williams Memorial Medical Center
Residency: University of Chicago Medical Center


American Brachytherapy Society, National American Cancer Society, LaGrange, Illinois Chapter, Local American College of Radiology, National American Society of Therapeutic Radiology and Oncology, National Smith County Medical Association, Local Society for Neuro-Oncology, National Texas Medical Association, Local


Dr. Kolker is a Penn Medicine employed physician.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.


Selected Publications:

Cheli CD, Levine RI, Cambetas DR, Kolker JD, Roberts SB.: Age-related reference ranges for complexed prostate-specific antigen and complexed/total prostate-specific antigen ratio: Results from East Texas Medical Center Cancer Institute screening campaign Urology 60(4 Suppl 1) : 53-9,2002.

Kolker JD, Weichselbaum RR.: Brain tumor radiobiology Advances in Neuro-Oncology : 1997.

Yang FE, Vaida F, Ignacio L, Awan A, Culbert H, Nautiyal J, Kolker JD, Sutton H, Halpern H, Weichselbaum RR, Chen GTY, Vijayakumar S.: Acute toxicity in radiotherapy of prostate cancer: Results of a randomized study with and without beam's-eye view three-dimensional conformal therapy Rad Onc Investigations : 1996.

Kolker JD, Sharma J, Cruz R, Diamond AD: Sequence and unusual 3' flanking region of the rattRNA [Ser] Sec gene Gene 164 : 375-376,1995.

Krishnasamy S, Vokes EE, Dohrmann GJ, Mick R, Garcia JC, Kolker JD, Wollman RL, Hekmatpanah J, Weichselbaum RR.: Concomitant chemoradiotherapy, neutron boost, and adjuvant chemotherapy for anaplastic astrocytoma and glioblastoma multiforme Cancer Invest 13(5) : 453-459,1995.

Choi IS, Diamond AD, Kolker JD, Hatfield DL.: Reconstruction of the biosythetic pathway of selenocysteine tRNAs in Xenopus oocytes. Biochemistry 33 (2): 601-605,1994.

Vijayakumar S, Awan A, Karrison K, Culbert H, Chan S, Kolker JD, Low N, Halpern H, Rubin S, Chen GTY, et al.: Acute toxicity during external beam radiotherapy for localized prostate cancer: comparison of different techniques Int J Radiat Oncol Biol Phys 25 : 359-371,1993.

Vokes E, Krishnasamy S, Dolan E, Ratain M, Dohrmann G, Hekmatpanah J, Kolker J, Weichselbaum R, Schilsky R, Berezin F, Walter P, Charlette J.: 5-fluorouracil (5-FU), hydroxyurea (HU) with escalating doses of iododeoxyuridine (IUdR) and concomitant radiotherapy (XRT) for malignant gliomas: A clinical and pharmacological analysis. American Association of Cancer Research : 1992.

Kolker JD, Vokes EE.: Chemotherapy and radiation therapy in the treatment of malignant gliomas of the brain J Infus Chemother 2 : 45-54,1992.

Kies MS, Pelzer H, Kolker JD, Weichselbaum RR, Breit R.: Management of squamous cell carcinoma of the tongue Contemporary Oncol 2 : 55-59,1991.

Academic Contact Info

Penn Radiation Oncology
Pennsylvania Hospital
Widener Ground Level
800 Spruce Street

Philadelphia, PA 19107
Phone: (215) 829-3873
Patient appointments: 800-789-PENN (7366)

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