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Jeffrey A. Drebin, MD, PhD, FACS

Jeffrey A. Drebin, MD, PhD, FACS Surgeon

Chairman, Department of Surgery
John Rhea Barton Professor of Surgery

Dr. Drebin is a Penn Medicine employed physician.

About Dr. Jeffrey A. Drebin

Recognized annually in Philadelphia Magazine's Top Docs issue from 2007 through 2015

Recognized by America's Top Doctors, 2007, 2008, 2010, 2012-14

Recognized by Best Doctors in America 2007-2008, 2009-2010, 2011-2012, 2013-2014

Clinical Specialties


  • Surgery
    • Gastrointestinal Surgery

Programs & Centers:

  • Cancer
    • Gastrointestinal Cancer Program
  • Gastroenterology
    • Gastrointestinal Surgery Consultation

Board Certification:

  • Surgery, 1995

Clinical Expertise:

  • Acid Peptic Disorders
  • Adrenal Cancer
  • Adrenal Gland Tumors
  • Ampullary Cancer
  • Anal Cancer
  • appendectomy
  • appendectomy evaluation
  • Bile Duct Cancer
  • Bile Duct Tumor
  • biliary stenosis
  • biliary strictures
  • biliary surgery
  • Biliary Tract Disorders
  • bowel adhesions - minimally invasive treatment
  • Cancer Surgery
  • cholecystectomy - laparoscopic
  • cholecystectomy - minimally invasive
  • colectomy
  • Colon Cancer
  • colon surgery
  • Colorectal Surgery
  • duodenal ulcer
  • Esophageal Cancer
  • feeding tubes
  • Gallbladder Cancer
  • Gallbladder Disorders
  • gallbladder motility
  • Gallstones
  • gastrectomy
  • gastric acid secretion
  • gastritis
  • Gastroesophageal Reflux Disease (GERD)
  • gastrointestinal biopsy
  • gastrointestinal bleeding
  • Gastrointestinal Carcinoid Tumor
  • Gastrointestinal Disorders
  • Gastrointestinal Oncology
  • Gastrointestinal Surgery
  • gastrointestinal surgery - upper/lower
  • Gastrointestinal Tumor
  • Gastroparesis
  • gastrostomy tube placement
  • hepatic resection
  • hepatobiliary surgery
  • Hepatocellular Carcinoma (HCC)
  • hernia surgery
  • hernia surgery - incisional
  • hernia surgery - inguinal
  • hernia surgery - inguinal laparoscopic
  • hernia surgery - inguinal minimally invasive
  • hernia surgery - laparoscopic
  • Hickman catheter placement
  • intestinal surgery - laparoscopic
  • jejunostomy tube placement
  • Laparoscopic Appendectomy
  • laparoscopic diagnosis - minimally invasive
  • laparotomy staging - minimally invasive
  • Leiomyosarcoma (LMS)
  • liver - intraarterial chemotherapy
  • Liver Cancer
  • Liver Metastases (Secondary Liver Cancer)
  • liver resection - minimally invasive
  • liver tumor surgery
  • Liver Tumors
  • lobectomy
  • Metastasis Cancer
  • Neuroendocrine Tumors
  • pancreas biopsy
  • Pancreatic Cancer
  • pancreatic surgery
  • Pancreatitis
  • Paragangliomas
  • Peptic Ulcer Disease
  • Pheocromocytoma
  • port placement
  • Rectal Cancer
  • small bowel resection - minimally invasive
  • Small Intestine Cancer
  • Soft Tissue Sarcoma
  • soft tissue tumor
  • splenectomy - minimally invasive
  • Stomach (Gastric) Cancer

Practice Locations and Appointments

  • Gastrointestinal Surgery

    Perelman Center for Advanced Medicine West Pavilion, 4th Floor 3400 Civic Center Boulevard Philadelphia, PA 19104 800-789-PENN (7366)

    A facility of the Hospital of the University of Pennsylvania

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Care
  • Rail Road Medicare / Palmetto GBA
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: Harvard Medical School
Residency: Johns Hopkins Hospital
Fellowship: Johns Hopkins Hospital


American Association for the Advancement of Science, National American Association of Cancer Research, National American Board of Surgery, National American College of Surgeons Oncology Group, National American College of Surgeons, National American Hepato-Pancreato-Biliary Association, National American Medical Association, National American Surgical Association, National Association of Academic Surgeons, National Halsted Society, National Institute of Medicine of the National Academy of Science, National National Cancer Institute, National National Institutes of Health, National Philadelphia Academy of Surgery, Local Society for Surgery of the Alimentary Tract, National Society of Clinical Surgery, National Society of Surgical Oncology, National Society of University Surgeons, National Southern Surgical Association, Local Surgical Biology Club II, National

Hospital Affiliation

Dr. Drebin is a Penn Medicine employed physician.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.


Selected Publications:

Veeramachaneni N, Kubokura H, Lin L, Pippin J, Patterson A, Drebin JA, Battafarano R: Down-regulation of beta-catenin inhibits the growth of squamous esophageal carcinoma cells. Journal of Thoracic and Cardiovascular Surgery 127 (1): 92-98,2004.

Scheri R, Drebin, JA: Tumors of the small intestine Current Surgical Therapy, 9th Edition : 2004.

Strasberg SM, Drebin JA, Linehan D: Radical antegrade modular pancreato-splenectomy Surgery 135 (5): 521-527,2003.

Veeramachaneni NK, Pippin J, Mokadam N, Lin L, Winslow E, Drebin JA: Down-regulation of beta-catenin expression and inhibition of colon cancer growth by doxycycline Annual Meeting of the Society of University Surgeons : 2003.

Veeramachaneni NK, Pippin J, Mokadam N, Lin L, Winslow E, Drebin JA: Protein Kinase C-mediated down-regulation of beta-catenin in colon cancer cells by doxycycline Annual Meeting of the Society for Surgical Oncology : 2003.

Mukhopadhyay D, Jung J, Murmu N, Houchen C, Dieckgraefe B, Drebin J, Veeramachneni N, Henderson J, Shrikant A: Prostaglandin mediated radiopro-tection of colon cancer occurs by inhibition of the RNA binding protein CUGBP2 Annual Meeting of the American Gastroenterological Association : 2003.

Winslow ER, Pippin J, Veeramachaneni N, Lin L, Drebin JA: Enhanced activity against pancreatic cancer cells using combinations of HER2/neu antisense oligodeoxynu-cleotides and monoclonal antibodies Surgical Forum, Journal of the American College of Surgeons 197 (S): 84,2003.

Canter RJ, Kesmodel S, Mokadam N, Drebin J, Fraker D: Suppression of beta-catenin by antisense oligomers augments tumor response to isolated limb perfusion in a rodent model of adenomatous polyposis coli-mutant colon cancer Surgical Forum, Journal of the American College of Surgeons 197 (S): 85,2003.

Drebin JA, Strasberg SM: Tumors of the biliary tree Textbook of Gastroenterology, 4th Edition : 2234-2251,2003.

Vollmer C, Drebin JA, Middleton WD, Teefey SA, Linehan D, Soper NJ, Eagon CJ, Strasberg SM: Utility of staging laparoscopy in subsets of peripancreatic and biliary malignancies Annals of Surgery 235 (1): 1-7,2002.

Academic Contact Info

Hospital of the University of Pennsylvania
Department of Surgery
3400 Spruce Street, 4th Floor Silverstein Pavilion

Philadelphia, PA 19104
Phone: (215) 662-7539
Fax: (215) 614-0363
Patient appointments: 800-789-PENN (7366)

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