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Najjia N. Mahmoud, MD

Najjia N. Mahmoud, MD Surgeon

Chief, Division of Colon and Rectal Surgery
Associate Professor of Obstetrics and Gynecology
Associate Professor of Surgery at the Hospital of the University of Pennsylvania and the Pennsylvania Hospital

Dr. Mahmoud is a Penn Medicine employed physician.

About Dr. N Mahmoud

Recognized annually in Philadelphia Magazine's Top Docs issue from 2010 through 2015

Recognized by Best Doctors in America 2005-2006, 2007-2008, 2009-2010, 2011-2012, 2013-2014

Clinical Specialties


  • Surgery
    • Colon & Rectal Surgery

Programs & Services:

  • Cancer
    • Anal Cancer
    • Colon Cancer
    • Gastrointestinal Carcinoid Tumor
    • Rectal Cancer
    • Small Intestine Cancer
    • Stomach (Gastric) Cancer
  • Colon and Rectal Surgery

Board Certification:

  • Colon and Rectal Surgery, 2002
  • Surgery, 2001

Conditions & Treatments:

  • anal anastomosis - J pouch
  • Anal Cancer
  • Anal Fistula
  • anal surgery
  • Bile Duct Cancer
  • Cancer Surgery
  • colectomy
  • Colitis
  • colon biopsy
  • Colon Cancer
  • colon polyps
  • colon surgery
  • Colorectal Surgery
  • endorectal ultrasound
  • enterocele repair
  • Esophageal Cancer
  • Gallbladder Cancer
  • gastrointestinal bleeding
  • gastrointestinal cancer
  • Gastrointestinal Carcinoid Tumor
  • gastrointestinal malignancies
  • Gastrointestinal Surgery
  • Gastrointestinal Tumor
  • Hemorrhoids
  • hidradenitis
  • incontinence - female
  • incontinence - male
  • inflammatory bowel disease - surgery
  • intestinal diseases
  • Liver Cancer

Practice Locations and Appointments

  • Colon and Rectal Surgery

    Perelman Center for Advanced Medicine West Pavilion, 4th Floor 3400 Civic Center Boulevard Philadelphia, PA 19104 800-789-PENN (7366)

    A facility of the Hospital of the University of Pennsylvania

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Care
  • Rail Road Medicare / Palmetto GBA
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: Weill Medical College of Cornell University
Residency: NewYork-Presbyterian/Weill Cornell Medical Center
Fellowship: University of Minnesota Hospitals


Abramson Cancer Center, University of Pennsylvania, Cancer Control and Prevention Group, National American Association for Cancer Research #18115, National American Association of Women Surgeons, National American Board of Colon and Rectal Surgery Key Concept Committee, National American Board of Colon and Rectal Surgery Written Examination Committee, National American Board of Colon and Rectal Surgery, National American College of Surgeons Oncology Group-5614, National American College of Surgeons, Candidate Group, #03054474, National American Medical Association, American Medical Women’s Association, National American Society of Colon and Rectal Surgeons, National CALGB, Gastrointestinal Committee, National CALGB, Gastrointestinal Correlative Science, National Crohn’s and Colitis Foundation of America, National Dr. Foster GI Goal Member, National Gastrointestinal Steering Committee, NCI, Colon Cancer, National Halsted Society, National Onco-Link consultant, neoplastic diseases of the colon and rectum., International Pennsylvania Society of Colon and Rectal Surgeons, Local Philadelphia Academy of Surgery, Local Sigma Xi Research Society, National Society of Surgical Oncology, National ßßß Biological Honor Society, National Surgical Society of the Alimentary Tract, National


Dr. Mahmoud is a Penn Medicine employed physician.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.


Selected Publications:

Stein D, Mahmoud NN, Rose D, Anne P, Goldstein S, Isenberg G, Mitchell E, Fry RD.: A Longer Time Interval Between Completion of Neoadjuvant Chemoradiation and Surgical Resection Does not Improve Downstaging of Rectal Carcinoma. Proceedings of the American Society of Colon and Rectal Surgeons : 2002.

Weyant MJ, Carothers AM, Mahmoud NN, Bradlow HL, Remotti H, Bilinski RT, Bertagnolli MM.: Reciprocal Expression of ERalpha and ERbeta is Associated with Estrogen-Mediated Modulation of Intestinal Tumorigenesis. Cancer Research 61(6) : 2547-51,2001.

Mahmoud NN, Madoff RD, Rothernberger DA, Finne CO.: TEM Reduces the Incidence of Positive Margins Compared to Transanal Excision for Rectal Tumors. Proceedings of the American Society of Colon and Rectal Surgeons : 2001.

Mahmoud NN, Carothers AM, Grunberger D, Bilinski RT, Churchill MR, Martucci C, Newmark HL, Bertagnolli MM.: Phenolic Antioxidants Decrease Intestinal Tumors in an Animal Model of Familial Adenomatous Polyposis. Carcinogenesis 21(5) : 921-927,2000.

Mahmoud NN, Bilinski RT, Churchill MR, Edelmann W, Kucherlapati R, Bertagnolli MM.: Genotype-Phenotype Correlation in Murine Apc Mutation: Differences in Enterocyte Migration and Response to Sulindac. Cancer Research 59(2) : 353-359,1999.

Mahmoud NN, Mack CA, DeCosse JJ, Michaeli J, Bertagnolli MM.: Debulking of a Gastrointestinal Hemangioma Alleviates Coagulopathy Associated with Kasabach-Merritt Syndrome. Surgery 125(2) : 236-238,1999.

Mahmoud NN, Bilinski RT, Mestre J, Martucci C, Bertagnolli MM.: Administration of an Unconjugated Bile Acid Increases Duodenal Tumors in a Murine Model of Familial Adenomatous Polyposis. Carcinogenesis 20(2) : 101-105,1999.

Carothers AM, Chiao C, Barrett JC, Mahmoud NN, Weyant MJ, Bilinski RT, Churchill MR, Grunberger D, Bertagnolli MM.: Caffeic Acid Phenethyl Ester (CAPE) Prevents Tumors in Min/+ Mice and Regulates p53 Function In Vitro. International Society of Cancer Chemoprevention, Strang International Cancer Prevention Conference, November 14, 1998; Annals of the New York Academy of Science : 1999.

Carothers AM, Weyant MJ, Mahmoud NN, Bilinski RT, Bertagnolli MM.: Estrogen modulates intestinal tumorigenesis in vitro and in vivo. Proceedings of the American Association of Cancer Research 40 : 530,1999.

Mahmoud NN, Boolbol SK, Dannenberg AJ, Mestre JR, Bilinski RT, Martucci C, Newmark HL, Chadburn A, Bertagnolli MM: The Sulfide Metabolite of Sulindac Prevents Tumors and Restores Enterocyte Apoptosis in a Murine Model of Familial Adenomatous Polyposis. Carcinogenesis 19(1) : 87-91,1998.

Academic Contact Info

Division of Colorectal Surgery - Department of Surgery
Hospital of the University of Pennsylvania
4 Silverstein Pavilion
3400 Spruce Street

Philadelphia, PA 19104
Patient appointments: 800-789-PENN (7366)

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