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Thomas J. Guzzo, MD, MPH Physician

Associate Program Director, Urology
Vice Chief, Urology
Associate Professor of Urology in Surgery at the Hospital of the University of Pennsylvania

Dr. Guzzo is a Penn Medicine employed physician.

Clinical Specialties


  • Surgery
    • Urology and Urologic Surgery

Programs & Centers:

  • Cancer
    • Genitourinary Cancer Program
  • Urology
    • Urologic Oncology

Board Certification:

  • Urology, 2011

Clinical Expertise:

  • Adrenal Gland Tumors
  • Bladder Cancer
  • Bloodless Medicine
  • Cancer Clinical Trials
  • Cancer Surgery
  • Cancer Therapy
  • Kidney Cancer
  • metastatic adrenocortical carcinoma
  • Penile Cancer
  • Prostate Cancer
  • renal cell carcinoma
  • Robotic Surgery
  • Solid Tumors
  • Testicular Cancer
  • Testicular Mass
  • Transitional Cell Carcinoma (Urothelial Carcinoma)
  • Ureteral Cancer
  • urologic oncology
  • Urologic Tumor

Practice Locations and Appointments

  • Urology

    Perelman Center for Advanced Medicine West Pavilion, 3rd Floor 3400 Civic Center Boulevard Philadelphia, PA 19104 800-789-PENN (7366)

    A facility of the Hospital of the University of Pennsylvania

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Care
  • Rail Road Medicare / Palmetto GBA
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: Temple University School of Medicine
Residency: Hospital of the University of Pennsylvania
Fellowship: Johns Hopkins Hospital


American College of Surgeons, National American Medical Association, National American Urologic Association, National Bladder Cancer Advocacy Network, National Mid-Atlantic Section, American Urologic Association, Local Philadelphia Urologic Society, Local Prostate Cancer Foundation, National

Hospital Affiliation

Dr. Guzzo is a Penn Medicine employed physician.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.


Selected Publications:

Graves R, Laryngakis N, Malkowicz SB, Guzzo TJ.: Therapeutic options for men with castrate-resistant prostate cancer. Annals of Urology : 2015 (In press).

Guzzo TJ, Vaughn DJ.: Invasive and metastatic bladder cancer. Campbell-Walsh Urology, 11th Edition. : 2015 (In press).

Guzzo TJ. Kidney and ureter.: Kidney and ureter. Gray’s Anatomy, 41st Edition. : 2015 (In press).

Pietzak EJ, Guzzo TJ.: Carcinoma of the urethra (male and female). Glenn’s Urologic Surgery Textbook, 8th Edition. : 2015 (In press).

Fang P, Mick R, Deville C, Both S, Bekelman JE, Christodoleas JP, Guzzo TJ, Tochner Z, Hahn SM, Vapiwala N.: A case-matched study of toxicity outcomes after proton therapy and intensity-modulated radiation therapy for prostate cancer. Cancer 121 (7): 1118-1127,2015.

Christodouleas JP, Baumann BC, He J, Hwang WT, Tucker KN, Bekelman JE, Tangen CM, Lerner SP, Guzzo TJ, Malkowicz SB.: Optimizing bladder cancer locoregional failure risk stratification after radical cystectomy using SWOG 8710. Cancer. 120 (8): 1272-1280,2015.

Pietzak EJ, Sterling ME, Smith ZL, Malkowicz SB, Guzzo TJ.: Outcomes of radical cystectomy in potential candidates for bladder preservation therapy. Urology 85 (4): 869-875,2015.

Pietzak EJ, Van Arsdalen K, Patel K, Malkowicz SB, Wein AJ and Guzzo TJ.: Impact of race on selecting appropriate patients for active surveillance with seemingly low-risk prostate cancer. Urology 85 (2): 436-440,2015.

Sun F, Oyesanmi O, Fontanarosa J, Reston J, Guzzo TJ, Schoelles K: Therapies for clinically localized prostate cancer: Update of a 2008 systematic review [Internet]. Rockville, MD: Agency for Healthcare Research and Quality (US) : 2014.

Pietzak EJ, Hwang WT, Malkowicz SB and Guzzo TJ.: Factors influencing the length of stay after radical cystectomy: implications for cancer care and perioperative management. Annals of Surgical Oncology 21 (13): 4383-4389,2014.

Academic Contact Info

Division of Urology
Hospital of the University of Pennsylvania
3400 Spruce Street, 9th Floor Penn Tower

Philadelphia, PA 19104
Patient appointments: 800-789-PENN (7366)

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